In Vitro Glycosylation

The Aw Lab develops cell-free glycosylation technologies for the production of bespoke glycoproteins.

Research Overview

We develop in vitro glycosylation systems that enable the controlled assembly of glycoproteins outside living cells.

Our work combines enzyme engineering, glycoengineering and cell-free technologies to explore new approaches for glycoprotein production.

Research Themes

ost

OST Engineering

Developing oligosaccharyltransferase systems for efficient glycan transfer.

glycoeng

Glycoengineering

Designing glycoengineered strains for improved recombinant protein production.

cfgps

Cell-Free Glycosylation

Developing OST-enabled cell-free systems for the synthesis and glycosylation of bespoke proteins.

Explore Our Research